Truth About Fen-Phen Fenfluramine

A lot of controversy surrounds the topic of Fen-Phen, this controversy has translated into negativity which surrounds other appetite suppressant drugs especially Phentermine. Several of these negative myths about Phentermine diet pills have been fuelled by the effects of the Fen-Phen combination and its subsequent withdrawal from the U.S market.

History of Fen-Phen

Fen-Phen was developed as a cocktail combination of drugs to counter obesity. The combination came to light in the seventies when the product was widely advocated as a solution to obesity and a requirement for anybody serious about weight loss. Fen- Phen is a combination of two variants of appetite suppressant drugs Fenfluramine and Phentermine. The product was granted approval by the FDA in 1973 and subsequently introduced into the U.S market.

How Fenfluramine Works

Like Phentermine, Fenfluramine operates by promoting the release of neurotransmitters. The neurotransmitter released in this case is serotonin.  The release of serotonin depresses the central nervous system and it regulates the mood of the individual as well as the person’s appetite, thereby creating the appetite suppressant feeling that is essential in weight loss drugs. The aim was that in combining Fenfluramine with Phentermine the effects on weight loss would be two-fold. It would help people lose weight much faster.

The Problem The combination of both appetite suppressants worked well to promote weight loss and the product was marketed widely by its makers, doctors, nutritionist experts as well as patients taking the medication. After a period of years had gone by the FDA started to receive complaints from users of the drug combination of Fenfluramine and Phentermine especially women. Then nature of the complaint was that these users had started developing heart related diseases and were becoming increasingly hypertensive.

Subsequent complaints about the combination led the FDA to call for its withdrawal from the U.S market. The FDA findings noted that the Fenfluramine part of the cocktail was responsible for the adverse effects noted in the findings. The adverse effects were not caused by Phentermine but the rumors and myths following the incident fail to mention this dissociation between the two drugs. A number of online Phentermine forums and resources contain discussions about this issue as well as references to FDA findings on Phentermine. You can still buy Phentermine online or order Phentermine from conventional sources because Phentermine diets pills are still FDA approved and are the number one choice of diet suppressant pills among overweight people.